Pharmacology - Drug classes, mechanisms, side effects

Q1: Complete the blood pressure equation: Blood Pressure = {{1}} × {{2}}, where the first term equals heart rate × {{3}}, and the second term is affected by {{4}} diameter.

Q2: A patient presents to the emergency department with agitation, temperature of 39.8°C (103.6°F), profuse sweating, muscle rigidity, and hyperreflexia. They started taking an SSRI two weeks ago, and yesterday their friend gave them tramadol for back pain. What is the MOST likely diagnosis?

Q3: During the {{1}} phase of clinical drug trials, the new drug is tested in a small number of healthy volunteers to assess safety and determine appropriate dosing. Later, in the {{2}} phase, the drug is tested in a large number of patients with the target disease to confirm effectiveness and monitor side effects.

Q4: A hospitalized patient is receiving IV vancomycin for MRSA bacteremia. During the infusion, she develops flushing of the face and upper body, itching, and a drop in blood pressure (110/70 → 85/55 mmHg). The nurse calls you urgently. What is happening and what should you do?

Q5: A 29-year-old woman with depression is highly concerned about sexual side effects and weight gain from medication. She has no history of seizures or eating disorders. Which antidepressant would be the BEST choice?