Practice question from Creatinine Clearance & Dose Adjustments
For a patient on hemodialysis, drugs that are __ molecular weight, have protein binding, and are water-__ are most likely to be removed during dialysis.
Answer
["small","low","soluble"]
Explanation
The mnemonic 'SMALL' helps remember dialyzability factors: Small molecular weight, Minimal protein binding, Aqueous (water-soluble), Low volume of distribution, Likely to be removed. Drugs meeting these criteria often require post-dialysis supplemental doses.
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